The PJS gene and multiple sclerosis
Please don’t worry about getting multiple sclerosis (MS) because you have PJS!
Please read on if you're interested in the research linking the PJS gene (STK11) to MS.
Wednesday, April 15, 2015
Incidence of Thyroid Abnormalities in Peutz-Jeghers Syndrome
Dear PJS
friends,
Many of us
have reported thyroid abnormalities, including thyroid cancer, yet we’ve been offered
no recommended thyroid screening guidelines. My earlier report is here http://peutz-jeghersnews.blogspot.com/2014/10/peutz-jeghers-syndrome-and-thyroid.html
Dr.
Stratakis and other researchers at the USA NIH – http://clinicalstudies.info.nih.gov/detail/A_95-CH-0059.html
– have included PJS patients in their larger clinical study of those with familial
lentiginosis syndromes.
The
following report is about their 19 PJS patients (3 females, 16 males) who were
evaluated for thyroid abnormalities by ultrasound. 14 or 73.7% had
abnormalities. “hypoechoic regions (7), nodules (5), cysts (4), regions of
inhomogenous tissue (1), hyperechoic regions (1), and calcifications (1).”
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